Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.79 |
| ▸ | CSK | P41240 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 8/20 | 0.51 |
| ▸ | BCR | P11274 | 5/20 | 0.50 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.50 |
| ▸ | LYN | P07948 | 3/20 | 0.50 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | ARAF | P10398 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.50 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.50 |
| ▸ | ABL2 | P42684 | 1/20 | 0.50 |
| ▸ | FRK | P42685 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017753 | 0.95 | TMPRSS2 (0.87) | TMPRSS2CSKMAPK14ABL1BCR | |
| SCHEMBL22017401 | 0.87 | TMPRSS2 (0.68) | TMPRSS2ABL1BRAFRETKIT | |
| SCHEMBL22017239 | 0.86 | TMPRSS2 (0.70) | TMPRSS2ABL1BRAFRETKIT | |
| SCHEMBL22017242 | 0.86 | TMPRSS2 (0.65) | TMPRSS2ABL1BCRBRAFRET | |
| SCHEMBL22017757 | 0.85 | TMPRSS2 (0.67) | TMPRSS2ABL1BRAFRETKIT | |
| SCHEMBL22017407 | 0.84 | TMPRSS2 (0.66) | TMPRSS2ABL1BRAFRETKIT | |
| SCHEMBL22018089 | 0.81 | TMPRSS2 (0.68) | TMPRSS2ABL1BRAFRETKIT | |
| SCHEMBL22017590 | 0.80 | TMPRSS2 (0.68) | TMPRSS2ABL1BRAFRETKIT | |
| SCHEMBL22017588 | 0.80 | TMPRSS2 (0.64) | TMPRSS2CSKMAPK14ABL1BCR | |
| SCHEMBL22017586 | 0.79 | TMPRSS2 (0.57) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020098710-A1 | SUBSTITUTED BIS-ARYL AMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREFOR | 中国医学科学院医药生物技术研究所 | 2020-05-22 | — | — | WO | disclosed |