Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 1/20 | 0.58 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27049055 | 0.88 | PTGFR (0.73) | PTGFRMMP8HSD11B1MMP2MMP9 | |
| SCHEMBL3381107 | 0.88 | PTGFR (0.73) | PTGFRMMP8HSD11B1MMP2MMP9 | |
| SCHEMBL3382048 | 0.88 | PTGFR (0.73) | PTGFRMMP8HSD11B1MMP2MMP9 | |
| SCHEMBL22017043 | 0.85 | PTGFR (0.81) | PTGFRCCR5LMNAPOLBFKBP1A | |
| SCHEMBL3382579 | 0.81 | PTGFR (0.64) | PTGFRPRKACACDK8GSK3AGSK3B | |
| SCHEMBL3386103 | 0.81 | PTGFR (0.64) | PTGFRPRKACACDK8GSK3AGSK3B | |
| SCHEMBL3382557 | 0.81 | PTGFR (0.64) | PTGFRPRKACACDK8GSK3AGSK3B | |
| SCHEMBL3382653 | 0.81 | PTGFR (0.64) | PTGFRPRKACACDK8GSK3AGSK3B | |
| SCHEMBL3383620 | 0.81 | PTGFR (0.64) | PTGFRPRKACACDK8GSK3AGSK3B | |
| SCHEMBL3382831 | 0.80 | PTGFR (0.64) | PTGFRHSD11B1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524003-B2 | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof | ObsEva S.A. (CH) | 2022-12-13 | — | — | US | disclosed |
| US-20200155515-A1 | ALPHA-AMINO ESTERS OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | XOMA (US) LLC | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200155515-A1 | ALPHA-AMINO ESTERS OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | PGF, PTGER1, PTGER4 | PTGFR 6/4885CCR5 1085/4885LMNA 1791/4885 |
| US-11524003-B2 | Alpha-amino esters of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof | PGF, PTGER1, PTGER4 | PTGFR 6/4885CCR5 1085/4885LMNA 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.