SCHEMBL22017336

SCHEMBL22017336

C#CCOc1ccc2cc(NC(=O)/C=C\C(=O)OC)c(=O)oc2c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 14/20 0.61
MAOA P21397 8/20 0.61
CA12 O43570 3/20 0.49
CA4 P22748 3/20 0.49
CA9 Q16790 3/20 0.49
CA1 P00915 1/20 0.49
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
GLA P06280 2/20 0.47
GAA P10253 2/20 0.47
HPGD P15428 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22016810 0.82 MAOB (0.44) MAOBMAOAKDM4EALDH1A1GLA
SCHEMBL29331103 0.77 MAPT (0.47) MAOBMAOACA12CA4CA9
SCHEMBL29254676 0.74 MEN1 (0.48) KDM4EALDH1A1GAAHPGD
SCHEMBL27404104 0.73 MAOA (0.48) MAOBMAOACA12CA4CA9
SCHEMBL11502238 0.73 MAOB (0.66) MAOBMAOACA12CA4CA9
SCHEMBL11502161 0.72 MAOB (0.76) MAOBMAOACA12CA4CA9
SCHEMBL22017341 0.71 CA12 (0.66) MAOBMAOACA12CA4CA9
SCHEMBL11502126 0.70 MAOB (0.79) MAOBMAOACA12CA4CA9
SCHEMBL29331064 0.70 GSTP1 (0.44) MAOBMAOACA12CA4CA9
SCHEMBL11396698 0.68 ALDH1A1 (0.78) MAOBMAOACA12CA4CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129909-B2 Conjugate and block copolymer containing fluorescent chromophore and preparation method therefor and use thereof UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2021-09-28 US disclosed
US-20200155707-A1 CONJUGATE AND BLOCK COPOLYMER CONTAINING FLUORESCENT CHROMOPHORE AND PREPARATION METHOD THEREFOR AND USE THEREOF UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA (CN) 2020-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11129909-B2 Conjugate and block copolymer containing fluorescent chromophore and preparation method therefor and use thereof WEE1, FAR1, FURIN MAOB 1529/4885MAOA 2560/4885CA12 252/4885
US-20200155707-A1 CONJUGATE AND BLOCK COPOLYMER CONTAINING FLUORESCENT CHROMOPHORE AND PREPARATION METHOD THEREFOR AND USE THEREOF WEE1, FAR1, FURIN MAOB 1529/4885MAOA 2560/4885CA12 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.