Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 9/20 | 0.35 |
| ▸ | CTSK | P43235 | 5/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018692 | 0.88 | MAPK1 (0.37) | MAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22018667 | 0.87 | CA1 (0.41) | NAMPTMAPK1APOBEC3ACTDSP1APOBEC3G | |
| SCHEMBL22018327 | 0.86 | ALDH1A1 (0.33) | MAPK1APOBEC3ACTDSP1APOBEC3GCYP1A2 | |
| SCHEMBL22018099 | 0.85 | MAPK1 (0.35) | MAPK1APOBEC3ACTDSP1APOBEC3GCYP1A2 | |
| SCHEMBL22018315 | 0.83 | MEN1 (0.34) | EGLN1MAPK1APOBEC3ACTDSP1APOBEC3G | |
| SCHEMBL22018297 | 0.82 | BAZ2B (0.39) | EGLN1 | |
| SCHEMBL22018316 | 0.82 | MAPK1 (0.38) | MAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22017870 | 0.81 | MEN1 (0.38) | CTSLCTSKCTSS | |
| SCHEMBL22018322 | 0.81 | ACR (0.38) | NAMPT | |
| SCHEMBL22017886 | 0.79 | TP53 (0.42) | EGLN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |