Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 3/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 3/20 | 0.46 |
| ▸ | STAMBP | O95630 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22017894 | 0.82 | RAB9A (0.41) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL22017890 | 0.80 | NPC1 (0.53) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL22018316 | 0.77 | MAPK1 (0.38) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL22018099 | 0.75 | MAPK1 (0.35) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22018688 | 0.75 | MAPK1 (0.37) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL22018692 | 0.75 | MAPK1 (0.37) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL22018304 | 0.74 | GABRA5 (0.39) | SMN1; SMN2RAB9ANPC1CYP1A2CYP2C9 | |
| SCHEMBL24145392 | 0.73 | CA1 (0.37) | KMT2ACYP1A2CYP2C9CYP2C19L3MBTL1 | |
| SCHEMBL22018315 | 0.73 | MEN1 (0.34) | EGLN1NPC1MEN1KMT2ACYP1A2 | |
| SCHEMBL22018297 | 0.72 | BAZ2B (0.39) | EGLN1SMN1; SMN2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |