SCHEMBL22018045

SCHEMBL22018045

O=C(O)CC[n+]1ccc(C(=O)NC2CC2)cn1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NPC1 O15118 2/20 0.41
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SMYD3 Q9H7B4 7/20 0.40
CYP46A1 Q9Y6A2 1/20 0.38
PRKAB2 O43741 1/20 0.38
PRKAG1 P54619 1/20 0.38
PRKAA2 P54646 1/20 0.38
PRKAA1 Q13131 1/20 0.38
PRKAG3 Q9UGI9 1/20 0.38
PRKAG2 Q9UGJ0 1/20 0.38
PRKAB1 Q9Y478 1/20 0.38
GRM5 P41594 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22017879 0.95 GRM5 (0.43) ALDH1A1L3MBTL1NPC1RAB9AKMT2A
SCHEMBL22017880 0.94 GRM5 (0.44) ALDH1A1NPC1RAB9AKMT2ASMN1; SMN2
SCHEMBL22017866 0.89 ALDH1A1 (0.34) ALDH1A1L3MBTL1NPC1MEN1RAB9A
SCHEMBL22017868 0.88 ALDH1A1 (0.41) ALDH1A1L3MBTL1MEN1KMT2APRKAB2
SCHEMBL22017865 0.87 ALDH1A1 (0.31) ALDH1A1L3MBTL1SMYD3PRKAB2PRKAG1
SCHEMBL22017889 0.84 BRD4 (0.39) ALDH1A1
SCHEMBL22018649 0.83
SCHEMBL22017872 0.82 HDAC6 (0.39) SMN1; SMN2
SCHEMBL22018046 0.81 LMNA (0.41) ALDH1A1L3MBTL1NPC1MEN1RAB9A
SCHEMBL22018297 0.81 BAZ2B (0.39) SMN1; SMN2GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099367-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-05-22 WO disclosed