Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 7/20 | 0.48 |
| ▸ | NPY4R | P50391 | 7/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.48 |
| ▸ | NPY1R | P25929 | 5/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | RAMP3 | O60896 | 7/20 | 0.47 |
| ▸ | CALCR | P30988 | 7/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018348 | 0.93 | APLNR (0.49) | MAPK8MAPK9MAPK10KDM1ARAMP3 | |
| SCHEMBL22922808 | 0.93 | APLNR (0.49) | MAPK8MAPK9MAPK10KDM1ARAMP3 | |
| SCHEMBL22019459 | 0.93 | APLNR (0.49) | MAPK8MAPK9MAPK10KDM1ARAMP3 | |
| SCHEMBL22019191 | 0.92 | NPY2R (0.46) | NPY2RNPY4RNPY5RNPY1RRAMP3 | |
| SCHEMBL22922809 | 0.92 | NPY2R (0.46) | NPY2RNPY4RNPY5RNPY1RRAMP3 | |
| SCHEMBL30933117 | 0.91 | APLNR (0.47) | NPY2RNPY4RNPY5RNPY1RRAMP3 | |
| SCHEMBL22380787 | 0.91 | APLNR (0.47) | MAPK8MAPK9MAPK10KDM1ARAMP3 | |
| SCHEMBL22019186 | 0.90 | APLNR (0.47) | MAPK8MAPK9MAPK10KDM1ARAMP3 | |
| SCHEMBL22380731 | 0.90 | KDM1A (0.53) | MAPK8MAPK9MAPK10KEAP1KDM1A | |
| SCHEMBL22018329 | 0.88 | NPY2R (0.47) | NPY2RNPY4RNPY5RNPY1RKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099925-A2 | PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES | YUYU PHARMA, INC. (KR) | 2020-05-22 | — | — | WO | disclosed |