SCHEMBL22380731

SCHEMBL22380731

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.53
▸ MAPK8 P45983 1/20 0.53
▸ MAPK9 P45984 1/20 0.53
▸ MAPK10 P53779 1/20 0.53
▸ KEAP1 Q14145 1/20 0.51
▸ REN P00797 5/20 0.50
▸ NMUR2 Q9GZQ4 1/20 0.49
▸ F2 P00734 2/20 0.49
▸ MAOB P27338 1/20 0.49
▸ KDM5A P29375 1/20 0.49
▸ KDM1B Q8NB78 1/20 0.49
▸ TACR1 P25103 1/20 0.49
▸ OPRD1 P41143 1/20 0.48
▸ TFPI P10646 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018606 0.92 OPRD1 (0.48) KEAP1RENNMUR2F2OPRD1
SCHEMBL30933098 0.91 REN (0.53) KEAP1RENNMUR2F2OPRD1
SCHEMBL29308367 0.91 BCL2L1 (0.48) KEAP1F2OPRD1TFPI
SCHEMBL22922808 0.91 APLNR (0.49) KDM1AMAPK8MAPK9MAPK10REN
SCHEMBL22019459 0.91 APLNR (0.49) KDM1AMAPK8MAPK9MAPK10REN
SCHEMBL22018348 0.91 APLNR (0.49) KDM1AMAPK8MAPK9MAPK10REN
SCHEMBL22019143 0.90 OPRD1 (0.56) KEAP1F2OPRD1
SCHEMBL22018355 0.90 MAPK8 (0.50) KDM1AMAPK8MAPK9MAPK10KEAP1
SCHEMBL30933101 0.89 REN (0.54) RENNMUR2F2OPRD1
SCHEMBL22380787 0.89 APLNR (0.47) KDM1AMAPK8MAPK9MAPK10REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR KDM1A 4761/4885MAPK8 2678/4885MAPK9 1074/4885
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR KDM1A 4761/4885MAPK8 2678/4885MAPK9 1074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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