SCHEMBL22018363

SCHEMBL22018363

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 5/20 0.48
▸ NTSR1 P30989 1/20 0.41
▸ NAA50 Q9GZZ1 1/20 0.41
▸ RAMP3 O60896 7/20 0.41
▸ CALCR P30988 7/20 0.41
▸ OPRD1 P41143 3/20 0.41
▸ OPRM1 P35372 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ NMUR2 Q9GZQ4 1/20 0.40
▸ NMUR1 Q9HB89 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29308439 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL22018810 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL22018314 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL22018809 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL22018380 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL22018502 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL22018340 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL22018370 1.00 APLNR (0.48) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL25527059 0.99 APLNR (0.49) APLNRNTSR1NAA50RAMP3CALCR
SCHEMBL25527056 0.99 APLNR (0.49) APLNRNTSR1NAA50RAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2023-10-05 — — US disclosed
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2023-05-11 — — US disclosed
WO-2021191689-A2 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS YUYU PHARMA, INC. (KR) 2021-09-30 — — WO disclosed
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT YUYU PHARMA, INC. (KR) 2021-01-28 — — US disclosed
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-08-27 — — US disclosed
WO-2020099925-A2 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES YUYU PHARMA, INC. (KR) 2020-05-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312648-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885NTSR1 589/4885NAA50 3702/4885
US-20230146455-A1 TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS VIP, TSLP, IAPP APLNR 90/4885NTSR1 561/4885NAA50 3485/4885
US-20210024577-A1 NOVEL PEPTIDE AND PHARMACEUTICAL COMPOSITION FOR TREATING AN EYE DISEASE COMPRISING THE SAME AS AN ACTIVE PHARMACEUTICAL INGREDIENT VIP, NGLY1, PROKR1 APLNR 279/4885NTSR1 958/4885NAA50 4230/4885
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 APLNR 334/4885NTSR1 1091/4885NAA50 4530/4885
US-20200270306-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES VIP, IAPP, SCTR APLNR 85/4885NTSR1 589/4885NAA50 3702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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