Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203751 | 1.00 | PRSS1 (0.33) | PRSS1PRSS2PRSS3CSNK1ENR1H2 | |
| SCHEMBL981570 | 0.98 | PRSS1 (0.31) | PRSS1PRSS2PRSS3CSNK1ENR1H2 | |
| SCHEMBL2202022 | 0.97 | PRSS1 (0.35) | PRSS1PRSS2PRSS3CSNK1ENR1H2 | |
| SCHEMBL982147 | 0.97 | PRSS1 (0.35) | PRSS1PRSS2PRSS3CSNK1ENR1H2 | |
| SCHEMBL983760 | 0.95 | PRSS1 (0.33) | PRSS1PRSS2PRSS3CSNK1E | |
| SCHEMBL982090 | 0.94 | CA2 (0.32) | ALDH1A1 | |
| SCHEMBL983665 | 0.91 | PRSS1 (0.36) | PRSS1PRSS2PRSS3CSNK1ENR1H2 | |
| SCHEMBL982624 | 0.91 | PRSS1 (0.36) | PRSS1PRSS2PRSS3CSNK1EALDH1A1 | |
| SCHEMBL983748 | 0.91 | PRSS1 (0.36) | PRSS1PRSS2PRSS3CSNK1EALDH1A1 | |
| SCHEMBL15229802 | 0.90 | PRSS1 (0.37) | PRSS1PRSS2PRSS3CSNK1ENR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977504-B2 | Process for producing isocyanates and aromatic hydroxy compounds | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274047-A1 | PROCESS FOR PRODUCING OF ISOCYANATES AND AROMATIC HYDROXY COMPOUNDS | PAH, APEH, HPD | PRSS1 2705/4885PRSS2 2090/4885PRSS3 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.