Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALPG | P10696 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831464 | 0.86 | HTT (0.62) | LMNAHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL13831159 | 0.85 | LMNA (0.60) | LMNAHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL18559167 | 0.85 | LMNA (0.60) | LMNAHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL15983337 | 0.85 | LMNA (0.59) | LMNAHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL15983359 | 0.84 | ALDH1A1 (0.69) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL15983346 | 0.84 | LMNA (0.58) | LMNAHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL13831176 | 0.84 | ALDH1A1 (0.53) | LMNAHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL22019648 | 0.83 | ALDH1A1 (0.75) | LMNAHTTALDH1A1MAPTKMT2A | |
| SCHEMBL15983344 | 0.83 | LMNA (0.57) | LMNAHTTALDH1A1MAPTMAPK1 | |
| SCHEMBL13831180 | 0.83 | LMNA (0.57) | LMNAHTTALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |