Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018535 | 0.80 | CYP3A4 (0.48) | CYP3A4RORCALDH1A1POLBTSHR | |
| SCHEMBL15983300 | 0.79 | ALDH1A1 (0.63) | CYP3A4ALDH1A1POLBTSHRHTT | |
| SCHEMBL13832095 | 0.78 | MEN1 (0.65) | CYP3A4ALDH1A1POLBTSHRMEN1 | |
| SCHEMBL13831179 | 0.76 | KMT2A (0.51) | CYP3A4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL22018798 | 0.76 | CYP3A4 (0.42) | CYP3A4RORCALDH1A1POLBTSHR | |
| SCHEMBL13831297 | 0.76 | NPSR1 (0.64) | ALDH1A1POLBTSHRMEN1KMT2A | |
| SCHEMBL15983380 | 0.76 | MEN1 (0.53) | CYP3A4ALDH1A1POLBTSHRMEN1 | |
| SCHEMBL13831879 | 0.75 | POLB (0.63) | ALDH1A1POLBTSHRMEN1KMT2A | |
| SCHEMBL13831648 | 0.74 | MAPK1 (0.60) | ALDH1A1MEN1KMT2AMAPK1HTT | |
| SCHEMBL22018538 | 0.74 | SMN1; SMN2 (0.46) | CYP3A4ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20160244756-A1 | NOVEL FORMATS FOR ORGANIC COMPOUNDS FOR USE IN RNA INTERFERENCE | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2016-08-25 | — | — | US | disclosed |