Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832072 | 0.80 | ALDH1A1 (0.64) | ALDH1A1TSHRLMNAHTTPOLB | |
| SCHEMBL22018536 | 0.80 | CYP3A4 (0.47) | CYP3A4RORCKMT2AMEN1ALDH1A1 | |
| SCHEMBL15983266 | 0.79 | LMNA (0.62) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL13832074 | 0.78 | KMT2A (0.65) | CYP3A4NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13832149 | 0.77 | KMT2A (0.54) | CYP3A4NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13831269 | 0.77 | KMT2A (0.51) | CYP3A4NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL13831925 | 0.76 | KMT2A (0.64) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL13831272 | 0.76 | ALDH1A1 (0.64) | CYP3A4KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL13831613 | 0.75 | KMT2A (0.65) | KMT2AMEN1ALDH1A1TSHRLMNA | |
| SCHEMBL22018538 | 0.74 | SMN1; SMN2 (0.46) | CYP3A4KMT2AALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |