Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018050 | 0.82 | ALDH1A1 (0.47) | NPC1RAB9AALDH1A1KDM4EP4HTM | |
| SCHEMBL22018297 | 0.82 | BAZ2B (0.39) | KDM4EHTTHDAC2HDAC8HDAC6 | |
| SCHEMBL22018673 | 0.82 | APOBEC3A (0.52) | RAB9AHDAC2HDAC8HDAC6APOBEC3A | |
| SCHEMBL22018099 | 0.80 | MAPK1 (0.35) | KDM4EHDAC6APOBEC3AAPOBEC3GMAPT | |
| SCHEMBL22336368 | 0.79 | P4HTM (0.36) | ALDH1A1KDM4EP4HTMMAPTHPGD | |
| SCHEMBL22018672 | 0.79 | SMN1; SMN2 (0.47) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL22017886 | 0.78 | TP53 (0.42) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL22322580 | 0.78 | HCAR2 (0.39) | ALDH1A1KDM4EP4HTMMAPTHPGD | |
| SCHEMBL22018045 | 0.77 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL22322578 | 0.77 | KDM4E (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |