Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018680 | 0.87 | MAPK1 (0.39) | HPGDSALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL22017876 | 0.84 | HPGDS (0.40) | HPGDSALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL22018099 | 0.82 | MAPK1 (0.35) | HPGDSLMNAMAPTCYP1A2CYP2C19 | |
| SCHEMBL22018679 | 0.79 | CA12 (0.37) | HPGDSALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL22018321 | 0.79 | CA12 (0.35) | HPGDSALDH1A1TSHRCYP2C19KDM4E | |
| SCHEMBL22018105 | 0.77 | HPGDS (0.35) | HPGDSLMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL22018291 | 0.77 | HPGDS (0.35) | HPGDSLMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL22017878 | 0.77 | HPGDS (0.34) | HPGDSLMNAMAPTKDM4EHPGD | |
| SCHEMBL22018290 | 0.76 | CA12 (0.41) | HPGDSALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL22350875 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |