Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.61 |
| ▸ | DRD3 | P35462 | 5/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.61 |
| ▸ | HRH1 | P35367 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13522139 | 0.88 | HTR2A (0.68) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C | |
| SCHEMBL14281158 | 0.88 | ADRA2B (0.57) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C | |
| SCHEMBL17979351 | 0.87 | DRD2 (0.69) | CHRM2CHRM1DRD3DRD2CHRM3 | |
| SCHEMBL30483504 | 0.87 | DRD2 (0.69) | CHRM2CHRM1DRD3DRD2CHRM3 | |
| SCHEMBL10615952 | 0.86 | HTR2A (0.66) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C | |
| SCHEMBL12307218 | 0.85 | HTR2A (0.64) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C | |
| SCHEMBL12307238 | 0.85 | HTR2A (0.64) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C | |
| SCHEMBL12307233 | 0.85 | HTR2A (0.64) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C | |
| SCHEMBL3531558 | 0.83 | HTR2A (0.55) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C | |
| SCHEMBL13051501 | 0.83 | HTR2A (0.78) | HTR2ASLC6A4SLC6A2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |