SCHEMBL22019249

SCHEMBL22019249

CCCCC(CC)Cn1c(=O)c2ccc3c4ccccc4oc4c(C#Cc5ccc(N)s5)cc(c1=O)c2c43

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPT P10636 2/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
MEN1 O00255 1/20 0.32
TSHR P16473 1/20 0.32
XBP1 P17861 1/20 0.32
PPARG P37231 1/20 0.32
KMT2A Q03164 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
TP53 P04637 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018367 0.87 MEN1 (0.40) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL22018366 0.86 RAB9A (0.41) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL22019247 0.85 MAPT (0.33) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL22018214 0.84 NPC1 (0.30) NPC1RAB9A
SCHEMBL22018368 0.84 KDM4E (0.33) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL22018221 0.80
SCHEMBL20783954 0.78 HSD17B10 (0.41) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL22019251 0.77
SCHEMBL22019252 0.75 KDM4E (0.32) KDM4EALDH1A1GAAHPGDHSD17B10
SCHEMBL22585357 0.72 ALDH1A1 (0.37) KDM4EALDH1A1GAAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020099793-A1 NOVEL BENZOTHIOXANTHENE P-CONJUGATED MOLECULES FOR ENERGY STORAGE UNIVERSITE D'ANGERS (FR) 2020-05-22 WO disclosed