Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019409 | 0.85 | ALDH1A1 (0.36) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL13831993 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL13832015 | 0.78 | KMT2A (0.51) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL13832021 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL13831344 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL22019617 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL22018793 | 0.76 | TP53 (0.31) | ALDH1A1TP53LMNAHPGDKDM4E | |
| SCHEMBL15983259 | 0.75 | ALDH1A1 (0.49) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL13832031 | 0.74 | KMT2A (0.49) | ALDH1A1TP53HDAC2LMNAKMT2A | |
| SCHEMBL13831008 | 0.74 | GAA (0.53) | ALDH1A1TP53LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |