Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019410 | 0.85 | SMN1; SMN2 (0.41) | ALDH1A1TP53HPGDLMNAHDAC2 | |
| SCHEMBL13831993 | 0.82 | ALDH1A1 (0.51) | ALDH1A1TP53HPGDLMNAHDAC2 | |
| SCHEMBL22046600 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDLMNAHSD17B10KDM4E | |
| SCHEMBL22018966 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1TP53HPGDLMNAHDAC2 | |
| SCHEMBL22018989 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1TP53HPGDLMNAHSD17B10 | |
| SCHEMBL13832015 | 0.78 | KMT2A (0.51) | ALDH1A1TP53HPGDLMNAHDAC2 | |
| SCHEMBL13831344 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TP53HPGDLMNAHDAC2 | |
| SCHEMBL13832021 | 0.78 | ALDH1A1 (0.49) | ALDH1A1TP53HPGDLMNAHDAC2 | |
| SCHEMBL22019621 | 0.78 | ALDH1A1 (0.73) | ALDH1A1TP53HPGDLMNAHDAC2 | |
| SCHEMBL22019394 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HPGDLMNAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |