Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019367 | 0.87 | SLC27A1 (0.54) | TSHRALDH1A1RAB9AMAPTUSP2 | |
| SCHEMBL22018510 | 0.81 | TSHR (0.54) | TSHRALDH1A1RAB9AMAPTUSP2 | |
| SCHEMBL22018518 | 0.80 | ALDH1A1 (0.55) | TSHRALDH1A1TP53RAB9AMAPT | |
| SCHEMBL4215408 | 0.77 | ALDH1A1 (0.72) | TSHRALDH1A1MAPK1 | |
| SCHEMBL22018594 | 0.77 | ALDH1A1 (0.55) | TSHRALDH1A1RAB9AMAPTUSP2 | |
| SCHEMBL22018589 | 0.77 | ALDH1A1 (0.53) | TSHRALDH1A1RAB9AMAPTUSP2 | |
| SCHEMBL13831528 | 0.77 | TP53 (0.74) | TSHRALDH1A1TP53RAB9AMAPT | |
| SCHEMBL22019376 | 0.76 | SLC27A1 (0.54) | TSHRALDH1A1RAB9AMAPTUSP2 | |
| SCHEMBL22018592 | 0.76 | ALDH1A1 (0.54) | TSHRALDH1A1MAPTUSP2SLC27A1 | |
| SCHEMBL22019413 | 0.75 | TSHR (0.53) | TSHRALDH1A1RAB9AMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |