Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15983319 | 0.82 | ATM (0.55) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 | |
| SCHEMBL22019397 | 0.80 | KDM4E (0.63) | SMN1; SMN2ALDH1A1TSHRMAPTHPGD | |
| SCHEMBL22019387 | 0.79 | KMT2A (0.49) | SMN1; SMN2ALDH1A1TSHRUSP2GAA | |
| SCHEMBL13831436 | 0.72 | ATM (0.76) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 | |
| SCHEMBL14478840 | 0.72 | ALDH1A1 (0.74) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 | |
| SCHEMBL13832319 | 0.71 | POLB (0.59) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 | |
| SCHEMBL13831397 | 0.70 | ATM (0.72) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 | |
| SCHEMBL13831402 | 0.69 | POLB (0.55) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 | |
| SCHEMBL13832328 | 0.69 | POLB (0.61) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 | |
| SCHEMBL14478844 | 0.68 | ATM (0.69) | SMN1; SMN2ALDH1A1TSHRMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |