Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019389 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL22019401 | 0.83 | CPB1 (0.68) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL15983284 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL22019400 | 0.81 | LRRK2 (0.57) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL14478848 | 0.81 | KDM4E (0.81) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL22019405 | 0.80 | LRRK2 (0.58) | KDM4EALDH1A1KMT2AMEN1LRRK2 | |
| SCHEMBL22019384 | 0.80 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AHPGDMAPTHSD17B10 | |
| SCHEMBL22019393 | 0.76 | LRRK2 (0.54) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL22046601 | 0.73 | ALDH1A1 (0.56) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL13832067 | 0.72 | KMT2A (0.75) | KDM4EALDH1A1KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |