Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 11/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112803 | 0.91 | CACNA1I (0.42) | CACNA1IKCNH2CACNA1HCYP2D6ENPP2 | |
| SCHEMBL4278734 | 0.82 | CACNA1I (0.43) | CACNA1IKCNH2CACNA1HCYP2D6ENPP2 | |
| SCHEMBL4275836 | 0.77 | CACNA1I (0.46) | CACNA1IKCNH2CACNA1HCYP2D6ENPP2 | |
| SCHEMBL4272368 | 0.75 | CACNA1I (0.44) | CACNA1IKCNH2CACNA1HCYP2D6ENPP2 | |
| SCHEMBL4272767 | 0.75 | CACNA1I (0.42) | CACNA1IKCNH2CACNA1HCYP2D6ENPP2 | |
| SCHEMBL19112992 | 0.74 | CACNA1I (0.47) | CACNA1IKCNH2CACNA1HCYP2D6ENPP2 | |
| SCHEMBL19112805 | 0.74 | CACNA1I (0.48) | CACNA1IKCNH2CACNA1HCYP2D6ENPP2 | |
| SCHEMBL4270993 | 0.72 | CACNA1I (0.45) | CACNA1IKCNH2CACNA1HCYP2D6 | |
| SCHEMBL4269196 | 0.71 | CACNA1I (0.46) | CACNA1IKCNH2CACNA1HCYP2D6 | |
| SCHEMBL4275588 | 0.71 | CACNA1I (0.45) | CACNA1IKCNH2CACNA1HCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189839-B1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | PRAXIS PREC MEDICINES INC (US) | 2020-05-20 | — | — | EP | disclosed |