SCHEMBL4278734

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4275836	0.92	CACNA1I (0.46)	CACNA1IKCNH2NPC1RAB9AENPP2
	SCHEMBL19112803	0.91	CACNA1I (0.42)	CACNA1IKCNH2ENPP2BCHEACHE
	SCHEMBL4272767	0.91	CACNA1I (0.42)	CACNA1IKCNH2NPC1RAB9AENPP2
	SCHEMBL4272368	0.90	CACNA1I (0.44)	CACNA1IKCNH2NPC1RAB9AENPP2
	SCHEMBL19112992	0.86	CACNA1I (0.47)	CACNA1IKCNH2NPC1RAB9AENPP2
	SCHEMBL19112805	0.86	CACNA1I (0.48)	CACNA1IKCNH2NPC1RAB9AENPP2
	SCHEMBL4270993	0.83	CACNA1I (0.45)	CACNA1IKCNH2NPC1RAB9ACACNA1C
	SCHEMBL4269196	0.82	CACNA1I (0.46)	CACNA1IKCNH2NPC1RAB9ACACNA1C
	SCHEMBL22019440	0.82	CACNA1I (0.39)	CACNA1IKCNH2ENPP2BCHEACHE
	SCHEMBL4282732	0.81	CACNA1I (0.44)	CACNA1IKCNH2NPC1RAB9ACACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.