Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 8/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019137 | 0.88 | VNN1 (0.37) | VNN1MLYCDDRD2LOXL2SIGMAR1 | |
| SCHEMBL21962810 | 0.81 | VNN1 (0.39) | VNN1MLYCDDRD2LOXL2LMNA | |
| SCHEMBL22020078 | 0.81 | VNN1 (0.39) | VNN1MLYCDDRD2LOXL2LMNA | |
| SCHEMBL21962749 | 0.81 | VNN1 (0.38) | VNN1MLYCDLOXL2RAF1BRAF | |
| SCHEMBL21962640 | 0.81 | VNN1 (0.38) | VNN1MLYCDLOXL2RAF1BRAF | |
| SCHEMBL22020542 | 0.81 | VNN1 (0.38) | VNN1MLYCDLOXL2RAF1BRAF | |
| SCHEMBL22019142 | 0.80 | VNN1 (0.38) | VNN1MLYCDLOXL2LMNA | |
| SCHEMBL21962621 | 0.80 | VNN1 (0.38) | VNN1MLYCDLOXL2LMNA | |
| SCHEMBL21962565 | 0.80 | RAF1 (0.42) | VNN1MLYCDLOXL2RAF1BRAF | |
| SCHEMBL22020520 | 0.80 | RAF1 (0.42) | VNN1MLYCDLOXL2RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |