Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 8/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020078 | 1.00 | VNN1 (0.39) | VNN1AOC3DPP4MLYCDDPP8 | |
| SCHEMBL22019142 | 0.97 | VNN1 (0.38) | VNN1AOC3DPP4MLYCDDPP8 | |
| SCHEMBL21962621 | 0.97 | VNN1 (0.38) | VNN1AOC3DPP4MLYCDDPP8 | |
| SCHEMBL22019137 | 0.88 | VNN1 (0.37) | VNN1MLYCDLOXL2LMNATSHR | |
| SCHEMBL22019323 | 0.88 | VNN1 (0.39) | VNN1AOC3MLYCDIRAK4LMNA | |
| SCHEMBL21962563 | 0.88 | VNN1 (0.39) | VNN1AOC3MLYCDIRAK4LMNA | |
| SCHEMBL21962682 | 0.84 | NR1H2 (0.39) | MLYCD | |
| SCHEMBL22019320 | 0.84 | NR1H2 (0.39) | MLYCD | |
| SCHEMBL21962461 | 0.83 | AKR1C3 (0.39) | VNN1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL21962778 | 0.81 | MLYCD (0.48) | VNN1MLYCDLMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | claimed |
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |