Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13830991 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2GAAALDH1A1TP53HTT | |
| SCHEMBL22018966 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ADRB2APOBEC3AAPOBEC3GGAA | |
| SCHEMBL15983372 | 0.80 | GAA (0.44) | ADRB2APOBEC3AAPOBEC3GGAAALDH1A1 | |
| SCHEMBL22018576 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2ADRB2APOBEC3AAPOBEC3GGAA | |
| SCHEMBL13830838 | 0.79 | GAA (0.47) | SMN1; SMN2GAAALDH1A1TP53HTT | |
| SCHEMBL22019617 | 0.79 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22018988 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2ADRB2APOBEC3AAPOBEC3GGAA | |
| SCHEMBL22019394 | 0.77 | ALDH1A1 (0.54) | SMN1; SMN2GAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22019410 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2ADRB2APOBEC3AAPOBEC3GGAA | |
| SCHEMBL13832323 | 0.76 | LMNA (0.44) | GAAALDH1A1TP53LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |