Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019778 | 0.80 | MEN1 (0.37) | MEN1KMT2ATSHRGAACYP1A2 | |
| SCHEMBL24978510 | 0.80 | MEN1 (0.37) | MEN1KMT2ATSHRGAACYP1A2 | |
| SCHEMBL22019756 | 0.80 | KDM4E (0.35) | MEN1KMT2ATSHRNPSR1KDM4E | |
| SCHEMBL21963080 | 0.79 | ACHE (0.46) | MEN1KMT2AKDM4E | |
| SCHEMBL24977974 | 0.77 | MEN1 (0.35) | MEN1KMT2AGAACYP1A2KDM4E | |
| SCHEMBL22020006 | 0.77 | TSHR (0.34) | MEN1KMT2ATSHRGAANPSR1 | |
| SCHEMBL24978135 | 0.75 | MEN1 (0.42) | MEN1KMT2ATSHRGAANPSR1 | |
| SCHEMBL22170105 | 0.71 | ACHE (0.48) | MEN1KMT2ATSHRGAANPSR1 | |
| SCHEMBL24871638 | 0.71 | KDM4E (0.33) | MEN1KMT2ATSHRNPSR1KDM4E | |
| SCHEMBL22020547 | 0.71 | NPSR1 (0.36) | MEN1KMT2ATSHRGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |