Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24978510 | 0.84 | MEN1 (0.37) | MEN1KMT2AKDM4EGAACYP1A2 | |
| SCHEMBL21963080 | 0.83 | ACHE (0.46) | MEN1KMT2AKDM4EACHEMAPK1 | |
| SCHEMBL22019727 | 0.80 | MEN1 (0.35) | MEN1KMT2AKDM4EGAACYP1A2 | |
| SCHEMBL24977974 | 0.80 | MEN1 (0.35) | MEN1KMT2AKDM4EGAACYP1A2 | |
| SCHEMBL22019726 | 0.80 | KDM4E (0.39) | MEN1KMT2AKDM4ECYP1A2ACHE | |
| SCHEMBL22020067 | 0.78 | KDM4E (0.36) | MEN1KMT2AKDM4ECYP1A2ACHE | |
| SCHEMBL22019776 | 0.74 | KDM4E (0.33) | MEN1KMT2AKDM4EGAACYP1A2 | |
| SCHEMBL22019783 | 0.73 | SMN1; SMN2 (0.40) | MEN1KMT2AKDM4ECYP1A2HSD17B10 | |
| SCHEMBL22019725 | 0.71 | CYP1A2 (0.33) | MEN1KMT2AKDM4EGAACYP1A2 | |
| SCHEMBL24162734 | 0.71 | ACHE (0.43) | MEN1KMT2AGAAACHEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |