Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22019851 | 0.83 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL21962068 | 0.79 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL21962067 | 0.79 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL20698783 | 0.76 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL20692347 | 0.75 | USP2 (0.39) | — | |
| SCHEMBL22020092 | 0.75 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL25033906 | 0.72 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL21963236 | 0.72 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL20681350 | 0.71 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL25067127 | 0.71 | PTGS2 (0.36) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |