⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285625 | 0.83 | — | — | |
| SCHEMBL5202776 | 0.80 | — | — | |
| SCHEMBL11398624 | 0.78 | MAPT (0.37) | — | |
| SCHEMBL13589000 | 0.78 | — | — | |
| SCHEMBL446876 | 0.78 | — | — | |
| SCHEMBL13262611 | 0.78 | — | — | |
| SCHEMBL972555 | 0.78 | — | — | |
| SCHEMBL6808774 | 0.78 | KMT2A (0.41) | — | |
| Hydrochloric Acid SCHEMBL5149348 | 0.77 | MAPT (0.36) | — | |
| SCHEMBL2994677 | 0.77 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230031406-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-02-02 | — | — | US | disclosed |
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |