Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020090 | 0.88 | CA2 (0.40) | CA2KDM4EGAA | |
| SCHEMBL20680928 | 0.83 | CA2 (0.36) | CA2KDM4EGAA | |
| SCHEMBL7144702 | 0.79 | CA2 (0.51) | CA2 | |
| SCHEMBL20692176 | 0.78 | CA2 (0.34) | CA2 | |
| SCHEMBL22013670 | 0.76 | CA2 (0.38) | CA2 | |
| SCHEMBL21810626 | 0.75 | NLRP3 (0.47) | CA2 | |
| SCHEMBL22021249 | 0.75 | CA2 (0.34) | CA2 | |
| SCHEMBL23482180 | 0.74 | NLRP3 (0.36) | — | |
| SCHEMBL26007201 | 0.74 | NLRP3 (0.36) | — | |
| SCHEMBL25085438 | 0.73 | NLRP3 (0.45) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102096-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |