SCHEMBL178733

SCHEMBL178733

O=C(NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.66
MDM2 Q00987 6/20 0.55
MDM4 O15151 1/20 0.54
TP53 P04637 1/20 0.54
TLR2 O60603 2/20 0.54
FOLH1 Q04609 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29528567 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL260631 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL178698 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29401258 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29359997 1.00 KMT2A (0.66) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29423590 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL29401604 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL119708 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL18148920 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2
SCHEMBL119709 0.97 KMT2A (0.64) KMT2AMDM2MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
EP-4748847-A1 PEPTIDE COMPLEX HAVING VEGFR -2 AGONIST ACTIVITY Peptidream Inc (JP) 2026-05-27 EP disclosed
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 US disclosed
US-20250282820-A1 PEPTIDE COMPLEX HAVING TRKB BINDING ACTIVITY PEPTIDREAM INC (JP) 2025-09-11 US disclosed
EP-4501941-A1 PEPTIDE COMPLEX HAVING TRKB BINDING ACTIVITY PeptiDream Inc. (JP) 2025-02-05 EP disclosed
US-20240209027-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION PEPTIAID INC (JP) 2024-06-27 US disclosed
EP-4317174-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION Peptiaid Inc (JP) 2024-02-07 EP disclosed
US-20230364255-A1 TRANSGLUTAMINASE-MEDIATED CONJUGATION HORIZON TECHNOLOGY FINANCE CORPORATION 2023-11-16 US disclosed
US-20230220005-A1 S100A8-INHIBITING PEPTIDE AND DISEASE THERAPEUTIC AGENT CONTAINING SAME TOKYO WOMEN'S MEDICAL UNIVERSITY (JP) 2023-07-13 US disclosed
US-20230220005-A1 S100A8-INHIBITING PEPTIDE AND DISEASE THERAPEUTIC AGENT CONTAINING SAME TOKYO WOMEN'S MEDICAL UNIVERSITY (JP) 2023-07-13 US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
WO-2012017021-A2 LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY GRAFFINITY PHARMACEUTICALS GMBH (DE) 2012-02-09 WO disclosed
US-6900213-B2 Bisaryl derivatives having FSH modulatory activity PHARMACOPEIA DRUG DISCOVERY, INC. (US) 2005-05-31 US disclosed
EP-1351941-B1 BISARYL DERIVATIVES HAVING FSH RECEPTOR MODULATORY ACTIVITY PHARMACOPEIA INC (US) 2004-09-29 EP disclosed
US-20040152703-A1 Bisaryl derivatives having FSH modulatory activity PHARMACOPEIA, LLC 2004-08-05 US disclosed
EP-1351941-A1 BISARYL DERIVATIVES HAVING FSH RECEPTOR MODULATORY ACTIVITY PHARMACOPEIA, INC. (US) 2003-10-15 EP disclosed
WO-2002070493-A1 BISARYL DERIVATIVES HAVING FSH RECEPTOR MODULATORY ACTIVITY PHARMACOPEIA, INC. (US) 2002-09-12 WO disclosed
US-5981500-A Antiparasitic agents related to the milbemycins and avermectins PFIZER INC. (US) 1999-11-09 US disclosed
EP-0677054-A1 NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS PFIZER INC. (US) 1995-10-18 EP disclosed
WO-1994015944-A1 NEW ANTIPARASITIC AGENTS RELATED TO THE MILBEMYCINS AND AVERMECTINS PFIZER LIMITED (GB) 1994-07-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 KMT2A 3715/4885MDM2 1169/4885MDM4 2010/4885
US-20040152703-A1 Bisaryl derivatives having FSH modulatory activity FSHR, GNRHR, LHCGR KMT2A 512/4885MDM2 2901/4885MDM4 4744/4885
US-20240209027-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION NGLY1, VIP, HM13 KMT2A 2534/4885MDM2 3700/4885MDM4 973/4885
US-20250282820-A1 PEPTIDE COMPLEX HAVING TRKB BINDING ACTIVITY NTRK2, BDNF, NPY1R KMT2A 1556/4885MDM2 3088/4885MDM4 4384/4885
US-20230220005-A1 S100A8-INHIBITING PEPTIDE AND DISEASE THERAPEUTIC AGENT CONTAINING SAME S100A8, S100A11, S100A4 KMT2A 3890/4885MDM2 733/4885MDM4 939/4885
US-20230364255-A1 TRANSGLUTAMINASE-MEDIATED CONJUGATION TGM2, TGM1, TGM6 KMT2A 995/4885MDM2 1020/4885MDM4 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.