Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19663401 | 0.83 | ELANE (0.46) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL7628046 | 0.82 | ELANE (0.45) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL18826239 | 0.80 | ELANE (0.47) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL19655518 | 0.75 | ELANE (0.39) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL15867625 | 0.74 | ELANE (0.61) | ELANELMNA | |
| SCHEMBL7276499 | 0.74 | ELANE (0.73) | ELANE | |
| SCHEMBL27584061 | 0.73 | HTR1D (0.46) | ELANE | |
| SCHEMBL1033055 | 0.72 | ELANE (0.51) | ELANECYP3A4CYP4F2CYP4A11 | |
| SCHEMBL28128282 | 0.72 | GUCY1A1 (0.33) | ELANEALDH1A1LMNACYP3A4CYP4F2 | |
| SCHEMBL9211912 | 0.71 | CCR5 (0.38) | ALDH1A1HIF1AAKT1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020101450-A1 | DERIVATIVE COMPOUNDS OF AZILSARTAN, INTERMEDIATES THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 엠에프씨 주식회사 | 2020-05-22 | — | — | WO | disclosed |