Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202201 | 1.00 | CYP19A1 (0.42) | CYP19A1MAOAMAOBAPPNQO2 | |
| SCHEMBL5787759 | 0.89 | MAPT (0.41) | CYP19A1MAPT | |
| SCHEMBL3048888 | 0.83 | MAPT (0.54) | MAOBMAPT | |
| SCHEMBL3048887 | 0.83 | MAPT (0.54) | MAOBMAPT | |
| SCHEMBL1983658 | 0.79 | TSHR (0.32) | MAPT | |
| SCHEMBL1356038 | 0.77 | ALDH1A1 (0.42) | MAPT | |
| SCHEMBL2721191 | 0.77 | ALDH1A1 (0.42) | — | |
| SCHEMBL15648671 | 0.73 | BDKRB2 (0.36) | CYP19A1MAPT | |
| SCHEMBL15648819 | 0.73 | BDKRB2 (0.36) | CYP19A1MAPT | |
| SCHEMBL25486381 | 0.73 | HTR2A (0.50) | CYP19A1MAOAMAOBAPPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11382991-B2 | Molecular probes for imaging of myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-07-12 | — | — | US | disclosed |
| US-20180339069-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | CASE WESTERN RESERVE UNIVERSITY | 2018-11-29 | — | — | US | disclosed |
| EP-2910945-B1 | Molecular probes for imaging of myelin | UNIV CASE WESTERN RESERVE (US) | 2018-07-18 | — | — | EP | disclosed |
| US-9987379-B2 | Molecular probes for imaging of myelin | CASE WESTERN RESERVE UNIVERSITY (US) | 2018-06-05 | — | — | US | disclosed |
| EP-2910945-A1 | Molecular probes for imaging of myelin | Case Western Reserve University (US) | 2015-08-26 | — | — | EP | disclosed |
| US-20140079635-A1 | MOLECULAR PROBES FOR DETECTING LIPID COMPOSITION | CASE WESTERN RESERVE UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20110189090-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | WANG YANMING | 2011-08-04 | — | — | US | disclosed |
| EP-2344877-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | Case Western Reserve University (US) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010039815-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | CASE WESTERN RESERVE UNIVERSITY (US) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140079635-A1 | MOLECULAR PROBES FOR DETECTING LIPID COMPOSITION | MAG, FABP7, PMP22 | CYP19A1 3731/4885MAOA 4823/4885MAOB 3390/4885 |
| US-20110189090-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | MAG, MYT1, PMP22 | CYP19A1 4876/4885MAOA 4725/4885MAOB 2851/4885 |
| US-20180339069-A1 | MOLECULAR PROBES FOR IMAGING OF MYELIN | MAG, MYT1, PMP22 | CYP19A1 4876/4885MAOA 4725/4885MAOB 2851/4885 |
| US-11382991-B2 | Molecular probes for imaging of myelin | MAG, MYT1, PMP22 | CYP19A1 4876/4885MAOA 4725/4885MAOB 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.