Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 19/20 | 0.62 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22021612 | 0.79 | ACLY (0.46) | ACLY | |
| SCHEMBL29985338 | 0.77 | ACLY (1.00) | ACLY | |
| SCHEMBL21961934 | 0.77 | ACLY (1.00) | ACLY | |
| SCHEMBL22021620 | 0.70 | ACLY (0.50) | ACLYCCR2 | |
| SCHEMBL1637774 | 0.68 | ACLY (0.53) | ACLYCCR2 | |
| SCHEMBL22005071 | 0.67 | ACLY (0.47) | ACLYCCR2 | |
| SCHEMBL21954763 | 0.65 | ACLY (1.00) | ACLY | |
| SCHEMBL21954759 | 0.65 | ACLY (1.00) | ACLY | |
| SCHEMBL21954738 | 0.62 | ACLY (1.00) | ACLY | |
| SCHEMBL11814974 | 0.59 | GRIK1 (0.42) | ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102616-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. (US) | 2020-05-22 | — | — | WO | disclosed |