Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 19/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22022211 | 0.79 | ACLY (0.62) | ACLY | |
| SCHEMBL21954750 | 0.76 | ACLY (0.73) | ACLY | |
| SCHEMBL22022216 | 0.69 | ACLY (0.60) | ACLY | |
| SCHEMBL31333146 | 0.67 | ACLY (0.44) | ACLY | |
| SCHEMBL8942357 | 0.66 | KMT2A (0.66) | ACLY | |
| SCHEMBL21954738 | 0.63 | ACLY (1.00) | ACLY | |
| SCHEMBL22003798 | 0.63 | ACLY (0.44) | ACLY | |
| SCHEMBL22022196 | 0.63 | KDM4E (0.46) | ACLY | |
| SCHEMBL8648612 | 0.63 | GRIK1 (0.65) | ACLYGRIK1GRIK2 | |
| SCHEMBL442742 | 0.61 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102616-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. (US) | 2020-05-22 | — | — | WO | disclosed |