Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | F11 | P03951 | 2/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587293 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL10700645 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL13146114 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL5520745 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL10582500 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL22992331 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL22984008 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL22983992 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL7151003 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 | |
| SCHEMBL8975481 | 0.86 | PTPN1 (0.57) | USP2KMT2AMEN1POLBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157138-A1 | NICOTINAMIDE ADENINE DINUCLEOTIDE ANALOGUES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157138-A1 | NICOTINAMIDE ADENINE DINUCLEOTIDE ANALOGUES | NAMPT, NNT, NNMT | USP2 4811/4885KMT2A 2184/4885MEN1 2452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.