Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.58 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527856 | 0.91 | EGFR (0.60) | EGFR | |
| SCHEMBL22821838 | 0.88 | EGFR (0.75) | EGFR | |
| SCHEMBL22026205 | 0.87 | EGFR (0.69) | EGFRINSRIGF1RALK | |
| SCHEMBL22025925 | 0.85 | EGFR (0.79) | EGFR | |
| SCHEMBL28525327 | 0.83 | EGFR (0.64) | EGFRINSRIGF1RALK | |
| SCHEMBL28542484 | 0.81 | EGFR (0.66) | EGFRINSRIGF1RALK | |
| SCHEMBL22821834 | 0.81 | EGFR (0.59) | EGFRINSRIGF1RALK | |
| SCHEMBL22822033 | 0.80 | EGFR (0.75) | EGFR | |
| SCHEMBL28542585 | 0.80 | EGFR (0.65) | EGFR | |
| SCHEMBL22822059 | 0.79 | EGFR (0.57) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513029-B | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-112513029-A | Nitrogen-containing aryl phosphorus oxide derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-03-16 | — | — | CN | disclosed |