SCHEMBL22028652

SCHEMBL22028652

CCCCCCCCCCCC(=O)NCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.58
CASP2 P42575 1/20 0.56
DNM1 Q05193 2/20 0.55
NAAA Q02083 1/20 0.53
EPHX2 P34913 3/20 0.50
SLC6A5 Q9Y345 2/20 0.49
LPAR1 Q92633 2/20 0.47
LPAR2 Q9HBW0 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
KDM4E B2RXH2 1/20 0.47
SELP P16109 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28260456 1.00 FAAH (0.58) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL29105419 1.00 FAAH (0.58) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL775223 1.00 FAAH (0.58) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL28414246 0.98 FAAH (0.56) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL31506253 0.95 CASP2 (0.59) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL31506279 0.95 CASP2 (0.59) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL31506304 0.95 CASP2 (0.59) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL28387442 0.94 CASP2 (0.61) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL21609561 0.94 CASP2 (0.61) FAAHCASP2DNM1NAAAEPHX2
SCHEMBL25768098 0.93 FAAH (0.47) FAAHCASP2DNM1NAAAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117019122-A Preparation method of novel hydrophilic alkyl bonded silica gel filler 苏州宇莘新材料有限公司 2023-11-10 CN claimed
CN-117019122-B Preparation method of hydrophilic alkyl bonded silica gel filler 苏州宇莘新材料有限公司 2024-07-19 CN disclosed
CN-117019122-A Preparation method of novel hydrophilic alkyl bonded silica gel filler 苏州宇莘新材料有限公司 2023-11-10 CN disclosed
US-11795058-B2 Silicon dioxide composite particle with far-infrared radioactivity; precursor of the same and application thereof NATIONAL CHI NAN UNIVERSITY (TW) 2023-10-24 US disclosed
US-11795058-B2 Silicon dioxide composite particle with far-infrared radioactivity; precursor of the same and application thereof NATIONAL CHI NAN UNIVERSITY (TW) 2023-10-24 US disclosed
WO-2021122431-A1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-24 WO disclosed
EP-3838964-A1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS Covestro Deutschland AG (DE) 2021-06-23 EP disclosed
CN-111285895-A Silicon dioxide composite particle with far infrared radiation, organic precursor thereof and application of composite particle 赖荣豊 2020-06-16 CN disclosed
US-20200180967-A1 SILICON DIOXIDE COMPOSITE PARTICLE WITH FAR-INFRARED RADIOACTIVITY; PRECURSOR OF THE SAME AND APPLICATION THEREOF Great Chain Chemical Ltd. (TW) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795058-B2 Silicon dioxide composite particle with far-infrared radioactivity; precursor of the same and application thereof MSR1, SIK2, FAR1 FAAH 2422/4885CASP2 1761/4885DNM1 4761/4885
US-20200180967-A1 SILICON DIOXIDE COMPOSITE PARTICLE WITH FAR-INFRARED RADIOACTIVITY; PRECURSOR OF THE SAME AND APPLICATION THEREOF MSR1, SIK2, FAR1 FAAH 2422/4885CASP2 1761/4885DNM1 4761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.