SCHEMBL22030366

SCHEMBL22030366

C=C(C)C(=O)OCCc1cc(-c2ccc3cc(C4CCC(C)CC4)ccc3c2)ccc1OCCO

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.34
MCHR1 Q99705 1/20 0.33
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.32
PPARD Q03181 9/20 0.31
PPARA Q07869 9/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PPARG P37231 3/20 0.31
ABL1 P00519 1/20 0.30
FPR2 P25090 1/20 0.30
SLC6A9 P48067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19804817 0.92 PPARG (0.37) CSF1RPPARDPPARAPPARGABL1
SCHEMBL19804075 0.92 CSF1R (0.35) CSF1RMCHR1CA1CA2TSHR
SCHEMBL19804725 0.88 MMP1 (0.33) CSF1RMCHR1CA1CA2TSHR
SCHEMBL19797141 0.87 PPARA (0.34) TSHRPPARDPPARAPPARGFPR2
SCHEMBL19803971 0.86 POLB (0.35) CSF1RMCHR1CA1CA2TSHR
SCHEMBL19624604 0.86 FFAR4 (0.35) CSF1RCA1CA2RAB9APOLB
SCHEMBL19624690 0.84 MCHR1 (0.35) CSF1RMCHR1CA1CA2TSHR
SCHEMBL19804069 0.84 SLC6A9 (0.39) CSF1RMCHR1CA1CA2TSHR
SCHEMBL19804134 0.83 CSF1R (0.40) CSF1RMCHR1CA1CA2TSHR
SCHEMBL19796666 0.83 CA1 (0.34) CSF1RMCHR1CA1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3656757-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2020-05-27 EP disclosed