Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999291 | 0.87 | GABRA5 (0.45) | ADRB3GABRA5GABRB2HSD17B10ALDH1A1 | |
| SCHEMBL11922835 | 0.83 | TDP1 (0.38) | NPC1RAB9APDE5ACHRM1AKR1A1 | |
| SCHEMBL31555036 | 0.81 | PDE5A (0.40) | PDE5ACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5514376 | 0.80 | PDE5A (0.37) | PDE5ACHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27684667 | 0.77 | HSD17B10 (0.43) | ADRB3GABRA5GABRB2HSD17B10ALDH1A1 | |
| SCHEMBL1565803 | 0.76 | HSD17B10 (0.46) | ADRB3GABRA5GABRB2HSD17B10ALDH1A1 | |
| SCHEMBL12877376 | 0.75 | NOS1 (0.41) | ADRB3GABRA5GABRB2HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1758691 | 0.75 | HSD17B10 (0.44) | ADRB3GABRA5GABRB2HSD17B10ALDH1A1 | |
| SCHEMBL9826899 | 0.75 | GABRA5 (0.40) | ADRB3GABRA5GABRB2HSD17B10ALDH1A1 | |
| SCHEMBL10506090 | 0.74 | HSD17B10 (0.47) | GABRA5GABRB2HSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345733-A1 | PROCESS FOR PRODUCING N-PROTECTED AMINO ACID | Kaneka Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |