Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 7/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421653 | 0.87 | CETP (0.49) | CETPCYP2C19CYP4F2CYP4A11MME | |
| SCHEMBL1421573 | 0.86 | CETP (0.45) | CETPCYP2C19CYP4F2CYP4A11 | |
| SCHEMBL1421937 | 0.84 | CETP (0.44) | CETPCYP2C19CYP4F2CYP4A11MME | |
| SCHEMBL9974581 | 0.83 | CETP (0.48) | CETPCYP2C19MME | |
| SCHEMBL1422218 | 0.83 | CETP (0.43) | CETPCYP2C19CYP4F2CYP4A11MME | |
| SCHEMBL1421785 | 0.83 | CETP (0.43) | CETPCYP2C19CYP4F2CYP4A11 | |
| SCHEMBL810162 | 0.81 | CETP (0.49) | CETPCYP2C19MME | |
| SCHEMBL727220 | 0.81 | CYP2C19 (0.50) | CETPCYP2C19MME | |
| SCHEMBL1421864 | 0.80 | CETP (0.41) | CETP | |
| SCHEMBL1534074 | 0.79 | CETP (0.48) | CETPCYP2C19MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150520-B1 | NOVEL PROCESS FOR THE PREPARATION OF ACID CHLORIDES | HOFFMANN LA ROCHE (CH) | 2012-10-31 | — | — | EP | disclosed |
| EP-1945601-B1 | NOVEL PROCESS FOR THE PREPARATION OF ACID CHLORIDES | HOFFMANN LA ROCHE (CH) | 2011-12-14 | — | — | EP | disclosed |
| US-7977509-B2 | Process for the preparation of acid halides | HOFFMANN-LA ROCHE INC. (US) | 2011-07-12 | — | — | US | disclosed |
| US-7728171-B2 | Process for the production of acid chlorides | HOFFMANN-LA ROCHE INC. (US) | 2010-06-01 | — | — | US | disclosed |
| EP-2150520-A1 | NOVEL PROCESS FOR THE PREPARATION OF ACID CHLORIDES | F. Hoffmann-Roche AG (CH) | 2010-02-10 | — | — | EP | disclosed |
| US-20090192333-A1 | PROCESS FOR THE PREPARATION OF ACID HALIDES | HOFFMANN URSULA | 2009-07-30 | — | — | US | disclosed |
| US-20090036703-A1 | PROCESS FOR THE PRODUCTION OF ACID CHLORIDES | HOFFMANN URSULA | 2009-02-05 | — | — | US | disclosed |
| WO-2008132044-A1 | NOVEL PROCESS FOR THE PREPARATION OF ACID CHLORIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-11-06 | — | — | WO | disclosed |
| US-20080269517-A1 | PROCESS FOR THE PREPARATION OF ACID HALIDES | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2008-10-30 | — | — | US | disclosed |
| US-7435849-B2 | Process for the production of acid chlorides | HOFFMANN-LA ROCHE INC. (US) | 2008-10-14 | — | — | US | disclosed |
| EP-1945601-A1 | NOVEL PROCESS FOR THE PREPARATION OF ACID CHLORIDES | F. Hoffmann-La Roche AG (CH) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051714-A1 | NOVEL PROCESS FOR THE PREPARATION OF ACID CHLORIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100154-A1 | Process for the production of acid chlorides | F. HOFFMANN-LA ROCHE AG (CH) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269517-A1 | PROCESS FOR THE PREPARATION OF ACID HALIDES | GBA1, ACAD9, CYP2F1 | CETP 3469/4885CYP2C19 72/4885CYP4F2 183/4885 |
| US-20070100154-A1 | Process for the production of acid chlorides | CLIC1, ACAD9, ASIC1 | CETP 3007/4885CYP2C19 56/4885CYP4F2 142/4885 |
| US-20090036703-A1 | PROCESS FOR THE PRODUCTION OF ACID CHLORIDES | CLIC1, ACAD9, ASIC1 | CETP 3007/4885CYP2C19 56/4885CYP4F2 142/4885 |
| US-20090192333-A1 | PROCESS FOR THE PREPARATION OF ACID HALIDES | GBA1, ACAD9, CYP2F1 | CETP 3469/4885CYP2C19 72/4885CYP4F2 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.