Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 2/20 | 0.47 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.42 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | IGF2R | P11717 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | GJA1 | P17302 | 1/20 | 0.37 |
| ▸ | GJB2 | P29033 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15393754 | 1.00 | FGF1 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL16508406 | 1.00 | FGF1 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL10014358 | 1.00 | FGF1 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL16500690 | 1.00 | FGF1 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL14255515 | 0.91 | LGALS3 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13560177 | 0.91 | LGALS3 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13867741 | 0.91 | LGALS3 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13559836 | 0.91 | LGALS3 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13560166 | 0.91 | LGALS3 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B | |
| SCHEMBL13559835 | 0.91 | LGALS3 (0.47) | FGF1LGALS9LGALS1LGALS3LGALS7; LGALS7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200164065-A1 | TRITERPENE SAPONIN ANALOGUES | ADJUVANCE TECHNOLOGIES, INC. (US) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200164065-A1 | TRITERPENE SAPONIN ANALOGUES | LSS, NFATC1, PGGT1B | FGF1 4700/4885LGALS9 1043/4885LGALS1 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.