SCHEMBL22031982

SCHEMBL22031982

C=CC(=O)OC=Cc1ccccc1.[Zn]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.44
HDAC3 O15379 3/20 0.44
HDAC4 P56524 3/20 0.44
HDAC2 Q92769 3/20 0.44
HDAC8 Q9BY41 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
LMNA P02545 3/20 0.44
MAPT P10636 3/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44
PLIN1 O60240 2/20 0.44
RECQL P46063 2/20 0.44
PLIN5 Q00G26 2/20 0.44
ABHD5 Q8WTS1 2/20 0.44
TNKS O95271 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
TNKS2 Q9H2K2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60238 0.98 LMNA (0.45) HDAC1HDAC3HDAC4HDAC2HDAC8
SCHEMBL195195 0.98 LMNA (0.45) HDAC1HDAC3HDAC4HDAC2HDAC8
Ammonia Solution, Strong SCHEMBL28427595 0.96 LMNA (0.44) HDAC1HDAC3HDAC4HDAC2HDAC8
SCHEMBL27604549 0.96 LMNA (0.44) HDAC1HDAC3HDAC4HDAC2HDAC8
SCHEMBL4354934 0.96 LMNA (0.44) HDAC1HDAC3HDAC4HDAC2HDAC8
SCHEMBL28836668 0.96 LMNA (0.44) HDAC1HDAC3HDAC4HDAC2HDAC8
Acrylic Acid SCHEMBL26674147 0.95 HDAC1 (0.47) HDAC1HDAC3HDAC4HDAC2HDAC8
SCHEMBL5311135 0.93 LMNA (0.41) HDAC1HDAC3HDAC4HDAC2HDAC8
Acrylic Acid SCHEMBL27621352 0.93 HDAC3 (0.46) HDAC1HDAC3HDAC4HDAC2HDAC8
SCHEMBL29011382 0.89 LMNA (0.40) HDAC1HDAC3HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12466929-B2 Ionomers of copolymers of vinylidene aromatic monomer and unsaturated compounds with acid groups TRINSEO EUROPE GMBH (CH) 2025-11-11 US disclosed
CN-113166466-B Ionomers of copolymers of vinylidene aromatic monomers with unsaturated compounds having acid groups 盛禧奥欧洲有限责任公司 2023-08-01 CN disclosed
US-20220056177-A1 IONOMERS OF COPOLYMERS OF VINYLIDENE AROMATIC MONOMER AND UNSATURATED COMPOUNDS WITH ACID GROUPS TRINSEO EUROPE GMBH (CH) 2022-02-24 US disclosed
EP-3891217-A1 IONOMERS OF COPOLYMERS OF VINYLIDENE AROMATIC MONOMER AND UNSATURATED COMPOUNDS WITH ACID GROUPS Trinseo Europe GmbH (CH) 2021-10-13 EP disclosed
CN-113166466-A Ionomers of copolymers of vinylidene aromatic monomers and unsaturated compounds having acid groups 盛禧奥欧洲有限责任公司 2021-07-23 CN disclosed
WO-2020115023-A1 IONOMERS OF COPOLYMERS OF VINYLIDENE AROMATIC MONOMER AND UNSATURATED COMPOUNDS WITH ACID GROUPS TRINSEO EUROPE GMBH (CH) 2020-06-11 WO disclosed