SCHEMBL4354934

SCHEMBL4354934

C=CC(=O)OC=Cc1ccccc1.[NaH]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
MAPT P10636 3/20 0.44
HDAC1 Q13547 3/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
PLIN1 O60240 2/20 0.44
RECQL P46063 2/20 0.44
PLIN5 Q00G26 2/20 0.44
ABHD5 Q8WTS1 2/20 0.44
CYP1A2 P05177 2/20 0.44
TNKS O95271 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
TNKS2 Q9H2K2 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60238 0.98 LMNA (0.45) LMNAMAPTHDAC1HDAC3HDAC4
SCHEMBL195195 0.98 LMNA (0.45) LMNAMAPTHDAC1HDAC3HDAC4
SCHEMBL27604549 0.96 LMNA (0.44) LMNAMAPTHDAC1HDAC3HDAC4
SCHEMBL22031982 0.96 HDAC1 (0.44) LMNAMAPTHDAC1HDAC3HDAC4
SCHEMBL28836668 0.96 LMNA (0.44) LMNAMAPTHDAC1HDAC3HDAC4
Ammonia Solution, Strong SCHEMBL28427595 0.96 LMNA (0.44) LMNAMAPTHDAC1HDAC3HDAC4
Acrylic Acid SCHEMBL26674147 0.95 HDAC1 (0.47) LMNAMAPTHDAC1HDAC3HDAC4
SCHEMBL5311135 0.93 LMNA (0.41) LMNAMAPTHDAC1HDAC3HDAC4
Acrylic Acid SCHEMBL27621352 0.93 HDAC3 (0.46) LMNAMAPTHDAC1HDAC3HDAC4
SCHEMBL29011382 0.89 LMNA (0.40) LMNAMAPTHDAC1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116998487-A Microcapsule containing pretilachlor and diflufenican as well as preparation method and application thereof 镇江先锋植保科技有限公司 2023-11-07 CN claimed
CN-115530160-A Dry propanil suspending agent and preparation method thereof 祥霖美丰生物科技(淮安)有限公司 2022-12-30 CN claimed
CN-115363040-A Suspending agent containing topramezone and amicarbazone and preparation method thereof 山东润博生物科技有限公司 2022-11-22 CN claimed
CN-112471143-A Microcapsule suspending agent of oxyfluorfen and metolachlor and preparation method thereof 上虞颖泰精细化工有限公司 2021-03-12 CN claimed
CN-116998487-A Microcapsule containing pretilachlor and diflufenican as well as preparation method and application thereof 镇江先锋植保科技有限公司 2023-11-07 CN disclosed
CN-114751438-B Alumina abrasive, preparation method, application, silicon wafer grinding fluid containing alumina abrasive and grinding method 浙江奥首材料科技有限公司 2023-09-08 CN disclosed
CN-115530160-A Dry propanil suspending agent and preparation method thereof 祥霖美丰生物科技(淮安)有限公司 2022-12-30 CN disclosed
CN-115363040-A Suspending agent containing topramezone and amicarbazone and preparation method thereof 山东润博生物科技有限公司 2022-11-22 CN disclosed
CN-114751438-A Aluminum oxide abrasive, preparation method and application thereof, silicon wafer grinding fluid containing aluminum oxide abrasive and grinding method 浙江奥首材料科技有限公司 2022-07-15 CN disclosed
CN-112471143-A Microcapsule suspending agent of oxyfluorfen and metolachlor and preparation method thereof 上虞颖泰精细化工有限公司 2021-03-12 CN disclosed
US-7538147-B2 Image forming method, pattern forming method and liquid-applying apparatus which make use of liquid compositions CANON KABUSHIKI KAISHA (JP) 2009-05-26 US disclosed
CN-101076561-A Stabilized organic materials containing fillers CIBA SC HOLDING AG (CH) 2007-11-21 CN disclosed
US-6494990-B2 HYDROPHILIC ACRYLAMIDE POLYMERS AND HYDROPHOBIC SURFACE SIZE AGENTS; NEWSPRINT PAPER BAYER CORPORATION 2002-12-17 US disclosed
US-20010051687-A1 METHODS AND AGENTS FOR IMPROVING PAPER PRINTABILITY AND STRENGTH KEMIRA OYJ (FI) 2001-12-13 US disclosed
EP-0846200-B1 METHODS AND AGENTS FOR IMPROVING PAPER PRINTABILITY AND STRENGTH BAYER AG (US) 2001-12-05 EP disclosed
US-6281291-B1 CROSSLINKED CARBOXYLATED POLYMER AND HYDROPHILIC POLYACRYLAMIDE BAYER CORPORATION 2001-08-28 US disclosed
US-6034181-A HYDROPHILIC ANIONIC POLYMERS CYTEC TECHNOLOGY CORP. (US) 2000-03-07 US disclosed
US-5824190-A APPLYING TO SURFACE A POLYMER LAYER AND POLYACRYLAMIDE FOR PAPER REINFORCEMENT CYTEC TECHNOLOGY CORP. (US) 1998-10-20 US disclosed
EP-0846200-A1 METHODS AND AGENTS FOR IMPROVING PAPER PRINTABILITY AND STRENGTH CYTEC TECHNOLOGY CORP. (US) 1998-06-10 EP disclosed
WO-1997008384-A1 METHODS AND AGENTS FOR IMPROVING PAPER PRINTABILITY AND STRENGTH CYTEC TECHNOLOGY CORP. (US) 1997-03-06 WO disclosed