Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | PDE5A | O76074 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30461668 | 0.86 | CYP1A2 (0.64) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL25260798 | 0.86 | CYP1A2 (0.64) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL4650589 | 0.83 | GABRP (0.61) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL27676687 | 0.82 | CYP1A2 (0.65) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL4649417 | 0.81 | CYP1B1 (0.63) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL8934600 | 0.81 | CYP19A1 (0.70) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL24046754 | 0.80 | CSNK2A2 (0.55) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL21822771 | 0.79 | CYP3A4 (0.67) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL29307653 | 0.78 | CYP1A2 (0.63) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 | |
| SCHEMBL13264829 | 0.78 | CYP1B1 (0.60) | CYP1B1CYP1A2CYP19A1CYP1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125811-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Ontrack Therapeutics Limited (GB) | 2025-06-19 | — | — | WO | disclosed |
| US-20210363124-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-11-25 | — | — | US | disclosed |
| EP-3891224-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | The Regents of the University of California (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020118116-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020118116-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363124-A1 | HETEROCYCLYL POLYMETHINE IR CHROMOPHORES | SMARCE1, CRY2, WDR82 | CYP1B1 3405/4885CYP1A2 3330/4885CYP19A1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.