Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 6/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MYLK | Q15746 | 1/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.42 |
| ▸ | XPO1 | O14980 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.40 |
| ▸ | ATF1 | P18846 | 4/20 | 0.40 |
| ▸ | JUN | P05412 | 4/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.40 |
| ▸ | RELA | Q04206 | 4/20 | 0.40 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032909 | 0.95 | P2RX1 (0.46) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL22033146 | 0.91 | TMPRSS4 (0.41) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL22033918 | 0.91 | MAPT (0.40) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL22033572 | 0.88 | MEN1 (0.45) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL22032991 | 0.88 | P2RX1 (0.38) | P2RX1P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL22033014 | 0.87 | RXFP1 (0.49) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL22032910 | 0.86 | P2RX1 (0.45) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL22033214 | 0.86 | TP53 (0.38) | P2RX1TMPRSS4MEN1KMT2ANFKB1 | |
| SCHEMBL22033253 | 0.86 | MEN1 (0.38) | P2RX1TMPRSS4P2RX4P2RX7MEN1 | |
| SCHEMBL22033344 | 0.84 | P2RX1 (0.40) | P2RX1P2RX4P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |