Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ATF1 | P18846 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033918 | 0.92 | MAPT (0.40) | MEN1KMT2ATMPRSS4RAB9ANPC1 | |
| SCHEMBL22033254 | 0.90 | TP53 (0.41) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL22032991 | 0.88 | P2RX1 (0.38) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL22033214 | 0.88 | TP53 (0.38) | MEN1KMT2ATMPRSS4RAB9ANPC1 | |
| SCHEMBL22033587 | 0.86 | RAB9A (0.34) | MEN1KMT2ATMPRSS4RAB9ANPC1 | |
| SCHEMBL22033143 | 0.86 | P2RX1 (0.42) | MEN1KMT2ATMPRSS4MAPTP2RX1 | |
| SCHEMBL22033228 | 0.85 | RIPK1 (0.38) | MEN1KMT2ATMPRSS4RAB9ANPC1 | |
| SCHEMBL22032878 | 0.85 | TP53 (0.39) | MEN1KMT2ARAB9ANPC1ATM | |
| SCHEMBL22032958 | 0.84 | FADS1 (0.44) | MEN1KMT2ARAB9ANPC1NPSR1 | |
| SCHEMBL22033344 | 0.84 | P2RX1 (0.40) | MEN1KMT2ARAB9ANPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |