Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203507 | 0.99 | KDM4E (0.33) | KDM4EMAPTESR2POLBALDH1A1 | |
| SCHEMBL2203504 | 0.81 | ALDH1A1 (0.39) | MAPTPOLBALDH1A1PKM | |
| SCHEMBL4947488 | 0.80 | POLB (0.35) | KDM4EMAPTPOLBALDH1A1PKM | |
| SCHEMBL2202381 | 0.79 | CYP1A2 (0.40) | KDM4EMAPTESR2POLBALDH1A1 | |
| SCHEMBL2203380 | 0.79 | CXCR4 (0.39) | KDM4EMAPTPOLBALDH1A1PKM | |
| SCHEMBL2202960 | 0.78 | CA2 (0.37) | SLC2A1CA1 | |
| SCHEMBL2203497 | 0.77 | SLC2A1 (0.35) | KDM4EMAPTESR2SLC2A1 | |
| SCHEMBL2204052 | 0.76 | CXCR4 (0.34) | SLC2A1 | |
| SCHEMBL2203348 | 0.72 | CA1 (0.43) | MAPTALDH1A1CA1MEN1MAPK1 | |
| SCHEMBL2204034 | 0.66 | CA2 (0.42) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977512-B2 | Amine derivative, and production method and use thereof | KUREHA CORPORATION (JP) | 2011-07-12 | — | — | US | disclosed |